How Psychogenetics &
Nutrigenomics Began
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RDS Genetic Testing
Genetic Testing is currently being in personalized medicine or treatments that are tailored to a person's genetic profile. At present many pharmaceutical and nutraceutical companies are spending millions of dollars in research and development to bring DNA customization to the customer and patients. Do not be fooled by other Genetic testing companies advertising on the internet. The product these companies peddle is called InfoGenetics. If the information they give is accurate the result is too often to scare the person because they offer no real treatments or plan of action.
DNA Customization of nutraceutical products is here. Discoveries by Kenneth Blum, Ph.D. and Ernie Noble, Ph.D. regarding the role of genes in determining craving behaviors opened new doors to understanding the genetic reasons why we do what we do and the influence that has on mental and physical health. Dr. Blum's patented nutraceutical technology (SynaptoseTM), to reduce or eradicate excessive cravings by influencing gene expression, pioneered the practical applications of nutrigenomics. His continuing discoveries and subsequent patents (and patents pending) have been an important catalyst for the evolution, expansion and scientific recognition of the significance of nutrigenomics and its remarkable contributions to human health. Neuro-Nutrigenomics is now a very important field of scientific investigation that offers great promise to improving the human condition.
What is the importance and value of DNA Customization (Why use it)?
While we all have basic similarities that may appear to make us pretty much the same, or at least make us need the same things in general, the fact is that there are many distinct differences within humans that can alter individual basic needs. Some of our most obvious differences include gender; age; race; body types; body sizes; tastes and appetites; physical and mental capabilities and activities; talents and skills; eye and hair color; blood types; etc. Other less obvious differences can influence our bodies and behaviors just as profoundly. Some of these differences include, among others, variations in:
Metabolic processes (the ability to produce and regulate energy)
Ability to tolerate stress
Emotions
Behaviors
Lifestyle- (i.e. food, drink and activity choices)
Immune system, etc.
What are the benefits of DNA Customization?
The wide range of variations in these differences creates a variety of differences in our individual needs. These differences result from genetic differences; that is variations in genotypes and their gene expressions (called polymorphisms). An example of this is that alcohol affects Asians and Native Americans quite differently than Caucasians. Genotypes represent specific gene variants. An individual is not and does NOT have only one genotype, but a vast number of genotypes. In order to effectively utilize DNA customization, it is necessary to know the many genotypes of an individual across multiple biological and metabolic pathways.
DNA customization eliminates the trial and error guesswork of finding the best product formulation for the individual, ensuring the greatest and most sustainable benefit. When done correctly, DNA Customization enables an individual to achieve levels of health, vitality, self-control, and happiness practically impossible without it.
DNA analysis and nutraceutical customization is a breakthrough technology. A number of companies have tried to achieve a commercial success with inferior versions of the technology and have either fallen short or failed. RDSolutions proprietary DNA Customized technology is unique, effective, and patented with additional patents pending.
Following is an overview of RDSolutions DNA customization process: Find the right science-based ingredients that influence therapeutically important pathways... a crucial factor. Existing research must validate the dose dependent mechanisms of action (MOA) and beneficial effects of those ingredients. Determine if, and by how much, those ingredients influence gene expression. Dose-dependent results are reviewed to establish the baseline dose needed to achieve beneficial gene-expression effects in a reasonable portion of the population. Research is then either conducted or, if available, reviewed to determine a range of dose-dependent gene expression results.
Dose-dependent gene-expression results are then compared to results in the MOA and efficacy research. Ingredients selected through this process become "DNA Qualified" and are used in DNA customized formulations. Research is then reviewed to determine which genotypes exhibit the kind of gene expressions noted in the gene expression studies.
Algorithms are then established for DNA Customized dose dependent applications for each DNA Qualified ingredient based on the genotypes for each pathway. Then research is reviewed or conducted on select populations of genotype-qualified candidates to confirm, and/or better define, and catalog the efficacy parameters. Once this process is completed, genuine DNA qualified ingredients can be customized for the gene polymorphisms of an individual. Specific genes of an individual are analyzed, via analysis of a buccal swab. Genotypes for crucial pathways are determined and ingredient potencies adjusted to accommodate gene-expression variations of the individual.
This is true DNA Customization.
Identifying these genetic and risk factors enables the use of the right products in the appropriate amounts to achieve the greatest benefits in the most people for the longest time. The problem is that we tend to look at 'what worked for somebody else' and then think that product will therefore work for me. DNA customization is the answer for the future in medicine and in nutritional health.
GENETIC ADDICTION RISK SCORE (GARS) ANALYSIS: EXPLORATORY DEVELOPMENT OF POLYMORPHIC RISK ALLELES IN POLY-DRUG ADDICTED MALES
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Reward Deficiency Solutions Systems
- Find out if you or your children have a genetic predisposition to RDS
- How to eliminate negative RDS behaviors; Stress, Craving, Depression or Anxiety
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Dr. Blum and Dr. Waite advocated a non-specific "healthy diet" and non-specific regular exercise to accompany a regimen of taking SynaptoseTM, the nutrigenomic neuroadaptogen they developed based on Dr. Blum's many years of research to increase the endogenous production of Dopamine and reduce negative Reward Deficiency Syndrome behaviors. The scientific evidence they have thus far accumulated, they say, demonstrates that SynaptoseTM changes the plasticity of the brain synapses while balancing the endogenous neurotransmitters, positively affecting the Brain Reward Cascade.
