How Psychogenetics &
Nutrigenomics Began
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Reward Deficiency Solutions Systems
- Find out if you or your children have a genetic predisposition to RDS
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New Paradigm in Cranial Electrical Treatments
Abstract
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The following data represents the pre to post EEG differences of an alcoholic in protracted abstinence. This subject was evaluated both before and after using a new paradigm in CES treatment
. The pre post comparisons suggest that the cortical potentials are up regulated after using the device which shows a decrease in the electrophysiological correlates of OCD, anxiety, impulsivity, and cravings in addicted populations.
Introduction
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Abundant research has established that an electroencephalogram (EEG) recorded from a healthy, normally functioning human has a predictable distribution of electrical power (measured in micro-volts squared), just as does the electrocardiogram, or EKG. The predictable electrical signals recorded by the EEG, distinctive for each brain region, are regulated by the homeostasis of a complex neuroanatomical brain system that utilizes all known neurotransmitters. Just as the EKG can be used to assess heart dysfunctions, the EEG can assess a wide variety of brain dysfunctions related to developmental, neurological and psychiatric disorders, whether caused by structural or functional abnormalities. Such assessment is called EEG Analysis.
Procedure
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Nineteen electrodes using an electro-cap consistent with the International 10/20 systems were placed. Routine EEG was recorded on a Cadwell Easy II using a linked ear montage and with electrodes digitally referenced to the Cz electrode allowing for retrospective montage analysis of all data. Using data gathered under technical conditions as listed above, 59.99 seconds of EEG were selected and subjected to quantitative analysis of absolute power, relative power, power asymmetry and coherence. These measurements are logarithmically transformed and referenced to age-adjusted population norms.
Findings
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Frequency band magnitude (uV) topographies of the EC condition are presented below.
Maps of EEG power spectra for bandranges
Fragment: , Offset: 0.00 s, Length: 59.99 s, Number of epochs 1.
The absolute power changes represented in the above images shows a decrease of more than 2 SD as noted in the delta wave spectrum. Also noted is an overall cortical increase in the alpha spectrum. The resting alert state of a neurotypical population is most prominently marked by a regulation of 7.5-11 Hz alpha throughout the cortex. The decreased in delta and theta suggests an up regulation of the prefrontal cortex and the anterior cingulate gyrus. A presence of dominant slow waves through the prefrontal cortex and the anterior cingulate gyrus is often associated with OCD, Anxiety, and impulsivity. To validate these findings a percentage change in microvolts squared was performed as presented by the below data.
Frequency band normalized power (% uV2) topographies for the EC condition are presented below.
Maps of EEG power spectra for bandranges
Fragment: , Offset: 0.00 s, Length: 59.99 s, Number of epochs 1.
The percentage of relative power change is congruent with the previous findings noting a 25% decrease in prefrontal delta and an increase in cortical potential marked by the prefrontal increase in activity throughout the theta and alpha spectrum. The overall alpha increase of 15-25% suggests an up regulation in post synaptic potentials noting that the brain has a more power to self regulate. In comparison to the aforementioned absolute power ranges these findings support the use of the CES technology in ameliorating the electrophysiological correlates of obsessive compulsion, anxiety, impulsivity, and cravings in addicted populations.
Publication pending
Synaptic Connection 2010
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Dr. Blum and Dr. Waite advocated a non-specific "healthy diet" and non-specific regular exercise to accompany a regimen of taking Synaptose
TM
, the nutrigenomic neuroadaptogen they developed based on Dr. Blum's many years of research to increase the endogenous production of Dopamine and reduce negative Reward Deficiency Syndrome behaviors. The scientific evidence they have thus far accumulated, they say, demonstrates that Synaptose
TM
changes the plasticity of the brain synapses while balancing the endogenous neurotransmitters, positively affecting the Brain Reward Cascade.
